Complete List of Published Work in MyBibliography:
Li, T.D., Toohill, K., Modzelewski, A.J. “From Junk DNA to Genomic Treasure: Impacts of Transposable Element DNA RNA and Protein in Mammalian Development and Disease” (In review at WIRES RNA, 2025)
Zhenlong Kang, Rui Guo, Shenglin Han, Fang Yang, Yuanyuan Wang2, Jinwen Zhang, Kara A Nelson1, Vamshidhar C. Nallamala, N. Adrian Leu, Zhengyi Li, Hongqing Liang, Yemin Lan, Anneliese Faustino, Hsin-Yao Tang, Andrew J. Modzelewski, Lan Ye*, P. Jeremy Wang* (2025) “Stage-dependent dual mechanisms of MORC2 functions in retrotransposon silencing and sex chromosome inactivation in germ cells” In Review at Nucleic Acids Research (NAR)
Guo, Y., Modzelewski, A.J. A retrotransposon caught red-handed in a curious case of missing digits. Nat Genet (2025).https://doi.org/10.1038/s41588-025-02147-9
Guo, Y., Li, T. D., Modzelewski, A. J. †, & Siomi, H. (2024). Retrotransposon renaissance in early embryos. Trends in Genetics, 0(0). https://doi.org/10.1016/J.TIG.2023.10.010
Rosas-Canyelles, E., Modzelewski, A. J., Geldert, A., He, L., Herr, A. E. Multimodal detection of protein isoforms and nucleic acids from mouse pre-implantation embryos Nature Protocols 16: 1062-1088, 2021.
Modzelewski, A. J., Shao, W., Chen, J., Lee, A., Qi, X., Noon, M., Tjokro, K., Sales, G., Biton, A., Anand, A., Speed, T. P., Xuan, Z., Wang, T., Risso, D., He, L. A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development Cell 184: 5541-5558.e22, 2021.
Tsitsiklis, A., Bangs, D. J., Lutes, L. K., Chan, S. W., Geiger, K. M., Modzelewski, A. J., Labarta-Bajo, L., Wang, Y., Zuniga, E. I., Dai, S., Robey, E. A. An unusual MHC molecule generates protective CD8+ T cell responses to chronic infection Frontiers in Immunology 11: 1464, 2020.
Rosas-Canyelles, E., Modzelewski, A. J., Geldert, A., He, L., Herr, A. E. Assessing heterogeneity among single embryos and single blastomeres using open microfluidic design Sci Adv 6: eaay1751, 2020.
Modzelewski, A. J., Chen, S., Willis, B. J., Lloyd, K. C. K., Wood, J. A., He, L. Efficient mouse genome engineering by CRISPR-EZ technology Nature Protocols 13: 1253-1274, 2018.
Hilz, S., Fogarty, E. A., Modzelewski, A. J., Cohen, P. E., Grimson, A. Transcriptome profiling of the developing male germ line identifies the miR-29 family as a global regulator during meiosis RNA Biology 14: 219-235, 2017.
Sun, X., Brieno-Enriquez, M. A., Cornelius, A., Modzelewski, A. J., Maley, T. T., Campbell-Peterson, K. M., Holloway, J. K., Cohen, P. E. FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice Chromosoma 125: 237-52, 2016.
Hilz, S., Modzelewski, A. J., Cohen, P. E., Grimson, A. The roles of microRNAs and siRNAs in mammalian spermatogenesis Development 143: 3061-73, 2016.
Chen, S., Lee, B., Lee, A. Y., Modzelewski, A. J., He, L. Highly efficient mouse genome editing by CRISPR ribonucleoprotein electroporation of zygotes Journal of Biological Chemistry 291: 14457-67, 2016.
Modzelewski, A. J., Hilz, S., Crate, E. A., Schweidenback, C. T., Fogarty, E. A., Grenier, J. K., Freire, R., Cohen, P. E., Grimson, A. Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males Journal of Cell Science 128: 2314-27, 2015.
Zhang, J., Bonasio, R., Strino, F., Kluger, Y., Holloway, J. K., Modzelewski, A. J., Cohen, P. E., Reinberg, D. SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors Genes & Development 27: 749-66, 2013.
Modzelewski, A. J., Holmes, R. J., Hilz, S., Grimson, A., Cohen, P. E. AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline Developmental Cell 23: 251-64, 2012.
Lyndaker, A. M., Modzelewski, A. J., Welsh, I. C. Reproductive and developmental genomics retreat at Cornell University, 2012 Molecular Reproduction and Development 79: 588-91, 2012.
Holloway, J. K., Mohan, S., Balmus, G., Sun, X., Modzelewski, A., Borst, P. L., Freire, R., Weiss, R. S., Cohen, P. E. Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis PLoS Genetics 7: e1002094, 2011.